Shiny Apps
Here is a short list of Shiny Apps that can be easily used to investigate targets and pathways of interest.
Enjoy!
ScRNAseq of myeloid cells from a mouse model of MS - Explore a shiny app obtained from the isolation of CX3CR1+ cells obtained from the experimental autoimmune encephalomyelitis (EAE) mouse model of MS, published in Peruzzotti-Jametti et al. Nature. 2024.
Bulk RNAseq of human iPS-derived microglia - Compare microglial transcriptomics in three protocols (Peruzzotti-Jametti et al. Nature. 2024, Chen et al. 2021, Guttikonda et al. 2021) vs post-mortem human microglia (Guttikonda et al. 2021).
SnRNAseq from MS brain white matter tissues - Explore a shiny app obtained from the re-analysis of data published in Absinta et al. Nature. 2021.
SnRNAseq from MS grey/brain white matter tissues - Find a detailed shiny app obtained from the re-analysis of data published in Schirmer et al. Nature. 2019.
Spatial LIBD - Spatial transcriptomics data from portion of the dorsolateral prefrontal cortex (DLPFC) that spans six neuronal layers plus white matter (Lieber Institute for Brain Development). Published in Huuki-Myers et al. Science 2024.
SnRNAseq of cerebral organoids - Shiny app to investigate cerebral organoid development and hetereogeneicity at single cell level (human, chimpanzee, and macaque), as described in Kanton, et al. Nature 2019.